This artwork features a central female figure, the Delphic Sibyl, sitting and holding an open scroll or book. She has a pensive, slightly turned expression, looking toward the left with her left arm extended to hold the pages of the open document. She wears a draped garment of terracotta red and mustard yellow, accented by a white cloth over her shoulders. Beside her, a cherubic figure holds a small, flaming dish or lamp, casting light upon the scene.
The setting is architectural, depicted in a classic High Renaissance fresco style. The background features light-toned, stone-like structures. Flanking the central figure are two pairs of nude, muscular putti or cherubs rendered in grisaille, appearing as sculptural relief decorations on the surrounding pillars. The composition is structured and balanced, typical of the grandeur of the Sistine Chapel.
The color palette is warm and earthen, dominated by soft shades of ochre, terracotta, tan, and muted blue-greys. The lighting is soft yet dramatic, emphasizing the volume and muscularity of the figures, which are rendered with clear, deliberate lines and a sense of weighty realism. The overall mood is classical, intellectual, and solemn, reflecting the high artistic standards of the early 16th century.